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Peptide record

TPDB00697

Antibacterial Anticancer Antifungal Antioxidant Antiparasitic Antiviral Toxicity standard
20 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB00697
Antibacterial Anticancer Antifungal Antioxidant Antiparasitic Antiviral Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides Functional / health-promoting peptides
AntiBP3 Peptipedia ACP740 _ACP240 AFP-GFuse Antifungipept CAFPdb dbAMP AODB Multi-AOP ToxinPred 3.0
standard
No
A 20-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, Peptipedia, ACP740 _ACP240, and other sources, with an available 3D structural model.
Sequence
GWANTLKNVAGGLCKITGAA
Physicochemical Analysis
C85H141N25O25S1
RDEQHMFPSY
AG
1945.27
9.90
2
0
9
+2
-0.99
0.365
93.00
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
5500
282.74
5
Residue Composition
number
4
A
0
R
2
N
0
D
1
C
0
E
0
Q
4
G
0
H
1
I
2
L
2
K
0
M
0
F
0
P
0
S
2
T
1
W
0
Y
1
V
Amino Acid Distribution
A: 4 R: 0 N: 2 D: 0 C: 1 E: 0 Q: 0 G: 4 H: 0 I: 1 L: 2 K: 2 M: 0 F: 0 P: 0 S: 0 T: 2 W: 1 Y: 0 V: 1
Chemical Descriptors
20
C85H141N25O25S1
1945.27
9.90
+2
-0.99
0.365
Evidence Records 18 records
Evidence 1 Activity

Activity

MIC
Antibacterial
37.5 µg/mL

Target

Staphylococcus aureus ATCC 2592

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
Active against Gram+ S. aureus ATCC 2592 (MIC 37.5 ug/ml) and E. faecium (MIC 37.5 ug/ml) and Gram- A. baumannii (MIC 37.5 ug/ml) and fungus C. alb
Evidence 2 Activity

Activity

MIC
Antibacterial
37.5 µg/mL

Target

E. faecium

Source & Reference

dbAMP

Other

Active against Gram+ S. aureus ATCC 2592 (MIC 37.5 ug/ml) and E. faecium (MIC 37.5 ug/ml) and Gram- A. baumannii (MIC 37.5 ug/ml) and fungus C. albicans ATCC 2002 (MIC 75 ug/ml),
Evidence 3 Activity

Activity

MIC
Antibacterial
37.5 µg/mL

Target

A. baumannii

Source & Reference

dbAMP

Other

inst Gram+ S. aureus ATCC 2592 (MIC 37.5 ug/ml) and E. faecium (MIC 37.5 ug/ml) and Gram- A. baumannii (MIC 37.5 ug/ml) and fungus C. albicans ATCC 2002 (MIC 75 ug/ml), but not active against other Gram+ E.fae
Evidence 4 Activity

Activity

MIC
Antibacterial
75 µg/mL

Target

Candida albicans ATCC 2002

Source & Reference

dbAMP

Other

ug/ml) and E. faecium (MIC 37.5 ug/ml) and Gram- A. baumannii (MIC 37.5 ug/ml) and fungus C. albicans ATCC 2002 (MIC 75 ug/ml), but not active against other Gram+ E.faecalis, N.asteroides, Gram- E.coli ATCC25922, S.m
Evidence 5 Activity

Activity

MIC
Antifungal
37.5 µg/mL

Target

Staphylococcus aureus ATCC 2592

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
Active against Gram+ S. aureus ATCC 2592 (MIC 37.5 ug/ml) and E. faecium (MIC 37.5 ug/ml) and Gram- A. baumannii (MIC 37.5 ug/ml) and fungus C. alb
Evidence 6 Activity

Activity

MIC
Antifungal
37.5 µg/mL

Target

E. faecium

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Active against Gram+ S. aureus ATCC 2592 (MIC 37.5 ug/ml) and E. faecium (MIC 37.5 ug/ml) and Gram- A. baumannii (MIC 37.5 ug/ml) and fungus C. albicans ATCC 2002 (MIC 75 ug/ml),
Evidence 7 Activity

Activity

MIC
Antifungal
37.5 µg/mL

Target

A. baumannii

Source & Reference

dbAMP CAFPdb Antifungipept

Other

inst Gram+ S. aureus ATCC 2592 (MIC 37.5 ug/ml) and E. faecium (MIC 37.5 ug/ml) and Gram- A. baumannii (MIC 37.5 ug/ml) and fungus C. albicans ATCC 2002 (MIC 75 ug/ml), but not active against other Gram+ E.fae
Evidence 8 Activity

Activity

MIC
Antifungal
75 µg/mL

Target

Candida albicans ATCC 2002

Source & Reference

dbAMP CAFPdb Antifungipept

Other

ug/ml) and E. faecium (MIC 37.5 ug/ml) and Gram- A. baumannii (MIC 37.5 ug/ml) and fungus C. albicans ATCC 2002 (MIC 75 ug/ml), but not active against other Gram+ E.faecalis, N.asteroides, Gram- E.coli ATCC25922, S.m
Evidence 9 Activity

Activity

MIC
Antiparasitic
37.5 µg/mL

Target

Staphylococcus aureus ATCC 2592

Source & Reference

NA

Other

Active against Gram+ S. aureus ATCC 2592 (MIC 37.5 ug/ml) and E. faecium (MIC 37.5 ug/ml) and Gram- A. baumannii (MIC 37.5 ug/ml) and fungus C. alb
Evidence 10 Activity

Activity

MIC
Antiparasitic
37.5 µg/mL

Target

E. faecium

Source & Reference

NA

Other

Active against Gram+ S. aureus ATCC 2592 (MIC 37.5 ug/ml) and E. faecium (MIC 37.5 ug/ml) and Gram- A. baumannii (MIC 37.5 ug/ml) and fungus C. albicans ATCC 2002 (MIC 75 ug/ml),
Evidence 11 Activity

Activity

MIC
Antiparasitic
37.5 µg/mL

Target

A. baumannii

Source & Reference

NA

Other

inst Gram+ S. aureus ATCC 2592 (MIC 37.5 ug/ml) and E. faecium (MIC 37.5 ug/ml) and Gram- A. baumannii (MIC 37.5 ug/ml) and fungus C. albicans ATCC 2002 (MIC 75 ug/ml), but not active against other Gram+ E.fae
Evidence 12 Activity

Activity

MIC
Antiparasitic
75 µg/mL

Target

Candida albicans ATCC 2002

Source & Reference

NA

Other

ug/ml) and E. faecium (MIC 37.5 ug/ml) and Gram- A. baumannii (MIC 37.5 ug/ml) and fungus C. albicans ATCC 2002 (MIC 75 ug/ml), but not active against other Gram+ E.faecalis, N.asteroides, Gram- E.coli ATCC25922, S.m
Evidence 13 Activity

Activity

MIC
Antiviral
37.5 µg/mL

Target

Staphylococcus aureus ATCC 2592

Source & Reference

NA

Other

Active against Gram+ S. aureus ATCC 2592 (MIC 37.5 ug/ml) and E. faecium (MIC 37.5 ug/ml) and Gram- A. baumannii (MIC 37.5 ug/ml) and fungus C. alb
Evidence 14 Activity

Activity

MIC
Antiviral
37.5 µg/mL

Target

E. faecium

Source & Reference

NA

Other

Active against Gram+ S. aureus ATCC 2592 (MIC 37.5 ug/ml) and E. faecium (MIC 37.5 ug/ml) and Gram- A. baumannii (MIC 37.5 ug/ml) and fungus C. albicans ATCC 2002 (MIC 75 ug/ml),
Evidence 15 Activity

Activity

MIC
Antiviral
37.5 µg/mL

Target

A. baumannii

Source & Reference

NA

Other

inst Gram+ S. aureus ATCC 2592 (MIC 37.5 ug/ml) and E. faecium (MIC 37.5 ug/ml) and Gram- A. baumannii (MIC 37.5 ug/ml) and fungus C. albicans ATCC 2002 (MIC 75 ug/ml), but not active against other Gram+ E.fae
Evidence 16 Activity

Activity

MIC
Antiviral
75 µg/mL

Target

Candida albicans ATCC 2002

Source & Reference

NA

Other

ug/ml) and E. faecium (MIC 37.5 ug/ml) and Gram- A. baumannii (MIC 37.5 ug/ml) and fungus C. albicans ATCC 2002 (MIC 75 ug/ml), but not active against other Gram+ E.faecalis, N.asteroides, Gram- E.coli ATCC25922, S.m
Evidence 17 Activity

Activity

2% Hemolysis
Toxicity
80 µg/mL
Hemolytic Cytotoxic
2% Hemolysis | 80 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Novel families of antimicrobial peptides with multiple functions from skin of Xizang plateau frog, Nanorana parkeri. | Biochimie | 2010
Evidence 18 Activity

Activity

11.3% degranulation
Toxicity
200 µg/mL
Cytotoxic
11.3% degranulation | 200 | µg/mL | target cell: Human mast cells

Target

Human mast cells

Source & Reference

NA
DBAASP
Novel families of antimicrobial peptides with multiple functions from skin of Xizang plateau frog, Nanorana parkeri. | Biochimie | 2010