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Peptide record

TPDB00635

Antibacterial Antifungal Antioxidant Hemolysis Toxicity standard
31 amino acids
Basic Information
3D PDB MODEL
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TPDB00635
Antibacterial Antifungal Antioxidant Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides Functional / health-promoting peptides
AntiBP3 Peptipedia Antifungipept CAFPdb dbAMP AODB APD_complete APD_hemolytic HemoPI Hemolytic2 PD_Hemolysis ToxinPred 3.0
standard
No
A 31-aa standard natural multi-activity (Antibacterial, Antifungal, Antioxidant, and other sources) peptide sequence curated from AntiBP3, Peptipedia, Antifungipept, and other sources, with an available 3D structural model.
Sequence
GLWNTIKEAGKKFALNLLDKIRCGIAGGCKG
Physicochemical Analysis
C146H244N42O39S2
QHMPSYV
G
3275.92
10.06
6
2
12
+4
2.91
-0.003
97.74
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
5625
171.71
5
Residue Composition
number
3
A
1
R
2
N
1
D
2
C
1
E
0
Q
6
G
0
H
3
I
4
L
5
K
0
M
1
F
0
P
0
S
1
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 3 R: 1 N: 2 D: 1 C: 2 E: 1 Q: 0 G: 6 H: 0 I: 3 L: 4 K: 5 M: 0 F: 1 P: 0 S: 0 T: 1 W: 1 Y: 0 V: 0
Chemical Descriptors
31
C146H244N42O39S2
3275.92
10.06
+4
2.91
-0.003
Evidence Records 22 records
Evidence 1 Activity

Activity

MIC
Antibacterial
>100 µM

Target

S.aureus ATCC 25923

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
Active against Gram+ S.aureus ATCC 25923 (MIC >100 uM), E. faecium 091299 (MIC 25 uM), E. faecalis 981 (MIC 100 uM), N. asteroides 201118 (MIC 6
Evidence 2 Activity

Activity

MIC
Antibacterial
25 µM

Target

E. faecium 091299

Source & Reference

dbAMP

Other

Active against Gram+ S.aureus ATCC 25923 (MIC >100 uM), E. faecium 091299 (MIC 25 uM), E. faecalis 981 (MIC 100 uM), N. asteroides 201118 (MIC 6.3 uM), Gram- P.aeruginosa CGMC
Evidence 3 Activity

Activity

MIC
Antibacterial
100 µM

Target

Enterococcus faecalis 981

Source & Reference

dbAMP

Other

Active against Gram+ S.aureus ATCC 25923 (MIC >100 uM), E. faecium 091299 (MIC 25 uM), E. faecalis 981 (MIC 100 uM), N. asteroides 201118 (MIC 6.3 uM), Gram- P.aeruginosa CGMCC 1.50 (MIC >100 uM), K. pneum
Evidence 4 Activity

Activity

MIC
Antibacterial
6.3 µM

Target

N. asteroides 201118

Source & Reference

dbAMP

Other

us ATCC 25923 (MIC >100 uM), E. faecium 091299 (MIC 25 uM), E. faecalis 981 (MIC 100 uM), N. asteroides 201118 (MIC 6.3 uM), Gram- P.aeruginosa CGMCC 1.50 (MIC >100 uM), K. pneumoniae 08040724 (MIC 100 uM), E.cloa
Evidence 5 Activity

Activity

MIC
Antibacterial
100 µM

Target

Klebsiella pneumoniae 08040724

Source & Reference

dbAMP

Other

100 uM), N. asteroides 201118 (MIC 6.3 uM), Gram- P.aeruginosa CGMCC 1.50 (MIC >100 uM), K. pneumoniae 08040724 (MIC 100 uM), E.cloacae CGMCC 1.57 (MIC >100 uM), E.coli ATCC 25922 (MIC >100 uM), P. faecalis X29 (MI
Evidence 6 Activity

Activity

MIC
Antibacterial
>100 µM

Target

E.coli ATCC 25922

Source & Reference

dbAMP

Other

0 (MIC >100 uM), K. pneumoniae 08040724 (MIC 100 uM), E.cloacae CGMCC 1.57 (MIC >100 uM), E.coli ATCC 25922 (MIC >100 uM), P. faecalis X29 (MIC 3.1 uM), and fungi C.glabrata 090902 (MIC >100 uM), C.albicans(ATCC
Evidence 7 Activity

Activity

MIC
Antibacterial
3.1 µM

Target

P. faecalis X29

Source & Reference

dbAMP

Other

040724 (MIC 100 uM), E.cloacae CGMCC 1.57 (MIC >100 uM), E.coli ATCC 25922 (MIC >100 uM), P. faecalis X29 (MIC 3.1 uM), and fungi C.glabrata 090902 (MIC >100 uM), C.albicans(ATCC 10231 (MIC>100 uM).
Evidence 8 Activity

Activity

MIC
Antibacterial
>100 µM

Target

C.glabrata 090902

Source & Reference

dbAMP

Other

7 (MIC >100 uM), E.coli ATCC 25922 (MIC >100 uM), P. faecalis X29 (MIC 3.1 uM), and fungi C.glabrata 090902 (MIC >100 uM), C.albicans(ATCC 10231 (MIC>100 uM).
Evidence 9 Activity

Activity

MIC
Antifungal
>100 µM

Target

S.aureus ATCC 25923

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
Active against Gram+ S.aureus ATCC 25923 (MIC >100 uM), E. faecium 091299 (MIC 25 uM), E. faecalis 981 (MIC 100 uM), N. asteroides 201118 (MIC 6
Evidence 10 Activity

Activity

MIC
Antifungal
25 µM

Target

E. faecium 091299

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Active against Gram+ S.aureus ATCC 25923 (MIC >100 uM), E. faecium 091299 (MIC 25 uM), E. faecalis 981 (MIC 100 uM), N. asteroides 201118 (MIC 6.3 uM), Gram- P.aeruginosa CGMC
Evidence 11 Activity

Activity

MIC
Antifungal
100 µM

Target

Enterococcus faecalis 981

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Active against Gram+ S.aureus ATCC 25923 (MIC >100 uM), E. faecium 091299 (MIC 25 uM), E. faecalis 981 (MIC 100 uM), N. asteroides 201118 (MIC 6.3 uM), Gram- P.aeruginosa CGMCC 1.50 (MIC >100 uM), K. pneum
Evidence 12 Activity

Activity

MIC
Antifungal
6.3 µM

Target

N. asteroides 201118

Source & Reference

dbAMP CAFPdb Antifungipept

Other

us ATCC 25923 (MIC >100 uM), E. faecium 091299 (MIC 25 uM), E. faecalis 981 (MIC 100 uM), N. asteroides 201118 (MIC 6.3 uM), Gram- P.aeruginosa CGMCC 1.50 (MIC >100 uM), K. pneumoniae 08040724 (MIC 100 uM), E.cloa
Evidence 13 Activity

Activity

MIC
Antifungal
100 µM

Target

Klebsiella pneumoniae 08040724

Source & Reference

dbAMP CAFPdb Antifungipept

Other

100 uM), N. asteroides 201118 (MIC 6.3 uM), Gram- P.aeruginosa CGMCC 1.50 (MIC >100 uM), K. pneumoniae 08040724 (MIC 100 uM), E.cloacae CGMCC 1.57 (MIC >100 uM), E.coli ATCC 25922 (MIC >100 uM), P. faecalis X29 (MI
Evidence 14 Activity

Activity

MIC
Antifungal
>100 µM

Target

E.coli ATCC 25922

Source & Reference

dbAMP CAFPdb Antifungipept

Other

0 (MIC >100 uM), K. pneumoniae 08040724 (MIC 100 uM), E.cloacae CGMCC 1.57 (MIC >100 uM), E.coli ATCC 25922 (MIC >100 uM), P. faecalis X29 (MIC 3.1 uM), and fungi C.glabrata 090902 (MIC >100 uM), C.albicans(ATCC
Evidence 15 Activity

Activity

MIC
Antifungal
3.1 µM

Target

P. faecalis X29

Source & Reference

dbAMP CAFPdb Antifungipept

Other

040724 (MIC 100 uM), E.cloacae CGMCC 1.57 (MIC >100 uM), E.coli ATCC 25922 (MIC >100 uM), P. faecalis X29 (MIC 3.1 uM), and fungi C.glabrata 090902 (MIC >100 uM), C.albicans(ATCC 10231 (MIC>100 uM).
Evidence 16 Activity

Activity

MIC
Antifungal
>100 µM

Target

C.glabrata 090902

Source & Reference

dbAMP CAFPdb Antifungipept

Other

7 (MIC >100 uM), E.coli ATCC 25922 (MIC >100 uM), P. faecalis X29 (MIC 3.1 uM), and fungi C.glabrata 090902 (MIC >100 uM), C.albicans(ATCC 10231 (MIC>100 uM).
Evidence 17 Activity

Activity

7% Hemolysis
Toxicity
6.3 µM
Hemolytic Cytotoxic
7% Hemolysis | 6.3 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Identification of multiple peptides with antioxidant and antimicrobial activities from skin and its secretions of Hylarana taipehensis, Amolops lifanensis, and Amolops granulosus. | Biochimie | 2014
Evidence 18 Activity

Activity

14% Hemolysis
Toxicity
12.5 µM
Hemolytic Cytotoxic
14% Hemolysis | 12.5 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Identification of multiple peptides with antioxidant and antimicrobial activities from skin and its secretions of Hylarana taipehensis, Amolops lifanensis, and Amolops granulosus. | Biochimie | 2014
Evidence 19 Activity

Activity

29% Hemolysis
Toxicity
25 µM
Hemolytic Cytotoxic
29% Hemolysis | 25 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Identification of multiple peptides with antioxidant and antimicrobial activities from skin and its secretions of Hylarana taipehensis, Amolops lifanensis, and Amolops granulosus. | Biochimie | 2014
Evidence 20 Activity

Activity

46% Hemolysis
Toxicity
50 µM
Hemolytic Cytotoxic
46% Hemolysis | 50 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Identification of multiple peptides with antioxidant and antimicrobial activities from skin and its secretions of Hylarana taipehensis, Amolops lifanensis, and Amolops granulosus. | Biochimie | 2014
Evidence 21 Activity

Activity

82% Hemolysis
Toxicity
100 µM
Hemolytic Cytotoxic
82% Hemolysis | 100 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Identification of multiple peptides with antioxidant and antimicrobial activities from skin and its secretions of Hylarana taipehensis, Amolops lifanensis, and Amolops granulosus. | Biochimie | 2014
Evidence 22 Hemolysis

Source & Reference

APD_complete APD_hemolytic HemoPI PD_Hemolysis
APD_complete APD_hemolytic PD_Hemolysis

Other

Source Activity Label Source Definition
Hemolysis
APD_complete APD-derived hemolytic peptide annotation. APD_hemolytic APD hemolytic peptide annotation.