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Peptide record

TPDB00616

Maximin 1 Antibacterial Anticancer Antifungal Antioxidant Antiparasitic Antiviral Hemolysis Toxicity standard
27 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB00616
Maximin 1
Antibacterial Anticancer Antifungal Antioxidant Antiparasitic Antiviral Hemolysis Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides Functional / health-promoting peptides
AntiBP3 dbAMP DRAMP Peptipedia ACP740 _ACP240 AntiCP 2.0 CancerPPD 2.0 SATPdb dbACP iACP-DRLF pep-lab AFP-GFuse Antifungipept CAFPdb dbAMP 3.0 AI4AVP AVPpred-BWR DRAVP 2.0 APD_complete APD_hemolytic Hemolytic2
standard
No
A 27-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
GIGTKILGGVKTALKGALKELASTYAN
Physicochemical Analysis
C120H208N32O36
RDCQHMFPW
G
2675.16
10.31
4
1
12
+3
2.59
0.252
112.22
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
1490
55.70
6
Residue Composition
number
4
A
0
R
1
N
0
D
0
C
1
E
0
Q
5
G
0
H
2
I
4
L
4
K
0
M
0
F
0
P
1
S
3
T
0
W
1
Y
1
V
Amino Acid Distribution
A: 4 R: 0 N: 1 D: 0 C: 0 E: 1 Q: 0 G: 5 H: 0 I: 2 L: 4 K: 4 M: 0 F: 0 P: 0 S: 1 T: 3 W: 0 Y: 1 V: 1
Chemical Descriptors
27
C120H208N32O36
2675.16
10.31
+3
2.59
0.252
Free
L
Not Available
Free
Anticancer
Bombina maxima
Evidence Records 32 records
Evidence 1 Activity

Activity

MIC
Antibacterial
19.5 µg/mL

Target

Escherichia coli ATCC25922

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class. DRAMP antibacterial activity supported by MIC records against bacterial target organisms.
Active against E. coli ATCC25922 (MIC 19.5 ug/ml), S. aureus ATCC2592 (MIC 19.5 ug/ml), B. pyocyaneus CMCCB10104 (MIC 19.5 ug/ml), B. megat
Evidence 2 Activity

Activity

MIC
Antibacterial
19.5 µg/mL

Target

Staphylococcus aureus ATCC2592

Source & Reference

dbAMP DRAMP

Other

Active against E. coli ATCC25922 (MIC 19.5 ug/ml), S. aureus ATCC2592 (MIC 19.5 ug/ml), B. pyocyaneus CMCCB10104 (MIC 19.5 ug/ml), B. megatherium (MIC 19.5 ug/ml), K. pneumonia
Evidence 3 Activity

Activity

MIC
Antibacterial
19.5 µg/mL

Target

B. pyocyaneus CMCCB10104

Source & Reference

dbAMP DRAMP

Other

Active against E. coli ATCC25922 (MIC 19.5 ug/ml), S. aureus ATCC2592 (MIC 19.5 ug/ml), B. pyocyaneus CMCCB10104 (MIC 19.5 ug/ml), B. megatherium (MIC 19.5 ug/ml), K. pneumoniae (MIC 9 ug/ml), B. dysenterium (MIC 2.7 uM
Evidence 4 Activity

Activity

MIC
Antibacterial
19.5 µg/mL

Target

B. megatherium

Source & Reference

dbAMP DRAMP

Other

5 ug/ml), S. aureus ATCC2592 (MIC 19.5 ug/ml), B. pyocyaneus CMCCB10104 (MIC 19.5 ug/ml), B. megatherium (MIC 19.5 ug/ml), K. pneumoniae (MIC 9 ug/ml), B. dysenterium (MIC 2.7 uM), C. albicans ATCC2002 (MIC 3 uM
Evidence 5 Activity

Activity

MIC
Antibacterial
9 µg/mL

Target

Klebsiella pneumoniae

Source & Reference

dbAMP DRAMP

Other

19.5 ug/ml), B. pyocyaneus CMCCB10104 (MIC 19.5 ug/ml), B. megatherium (MIC 19.5 ug/ml), K. pneumoniae (MIC 9 ug/ml), B. dysenterium (MIC 2.7 uM), C. albicans ATCC2002 (MIC 3 uM), A.flavus IFFI4015 (ND), an
Evidence 6 Activity

Activity

MIC
Antibacterial
2.7 µM

Target

B. dysenterium

Source & Reference

dbAMP DRAMP

Other

MCCB10104 (MIC 19.5 ug/ml), B. megatherium (MIC 19.5 ug/ml), K. pneumoniae (MIC 9 ug/ml), B. dysenterium (MIC 2.7 uM), C. albicans ATCC2002 (MIC 3 uM), A.flavus IFFI4015 (ND), and P.uticale IFFI2001 (ND). It
Evidence 7 Activity

Activity

MIC
Antibacterial
3 µM

Target

Candida albicans ATCC2002

Source & Reference

dbAMP DRAMP

Other

. megatherium (MIC 19.5 ug/ml), K. pneumoniae (MIC 9 ug/ml), B. dysenterium (MIC 2.7 uM), C. albicans ATCC2002 (MIC 3 uM), A.flavus IFFI4015 (ND), and P.uticale IFFI2001 (ND). It also has spermicidal effect. act
Evidence 8 Activity

Activity

Not Available
Anticancer

Target

Not Available
Not Available
Not Available

Assay & Model

Not Available
Not Available

Source & Reference

dbAMP 3.0 CancerPPD 2.0 dbACP SATPdb
CancerPPD2
2002

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation. dbAMP 3.0 classified as Anticancer under the disease-associated peptide function classes.
Evidence 9 Activity

Activity

MIC
Antifungal
19.5 µg/mL

Target

Escherichia coli ATCC25922

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class. DRAMP antifungal activity supported by activity records against fungal target organisms.
Active against E. coli ATCC25922 (MIC 19.5 ug/ml), S. aureus ATCC2592 (MIC 19.5 ug/ml), B. pyocyaneus CMCCB10104 (MIC 19.5 ug/ml), B. megat
Evidence 10 Activity

Activity

MIC
Antifungal
19.5 µg/mL

Target

Staphylococcus aureus ATCC2592

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Active against E. coli ATCC25922 (MIC 19.5 ug/ml), S. aureus ATCC2592 (MIC 19.5 ug/ml), B. pyocyaneus CMCCB10104 (MIC 19.5 ug/ml), B. megatherium (MIC 19.5 ug/ml), K. pneumonia
Evidence 11 Activity

Activity

MIC
Antifungal
19.5 µg/mL

Target

B. pyocyaneus CMCCB10104

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Active against E. coli ATCC25922 (MIC 19.5 ug/ml), S. aureus ATCC2592 (MIC 19.5 ug/ml), B. pyocyaneus CMCCB10104 (MIC 19.5 ug/ml), B. megatherium (MIC 19.5 ug/ml), K. pneumoniae (MIC 9 ug/ml), B. dysenterium (MIC 2.7 uM
Evidence 12 Activity

Activity

MIC
Antifungal
19.5 µg/mL

Target

B. megatherium

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

5 ug/ml), S. aureus ATCC2592 (MIC 19.5 ug/ml), B. pyocyaneus CMCCB10104 (MIC 19.5 ug/ml), B. megatherium (MIC 19.5 ug/ml), K. pneumoniae (MIC 9 ug/ml), B. dysenterium (MIC 2.7 uM), C. albicans ATCC2002 (MIC 3 uM
Evidence 13 Activity

Activity

MIC
Antifungal
9 µg/mL

Target

Klebsiella pneumoniae

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

19.5 ug/ml), B. pyocyaneus CMCCB10104 (MIC 19.5 ug/ml), B. megatherium (MIC 19.5 ug/ml), K. pneumoniae (MIC 9 ug/ml), B. dysenterium (MIC 2.7 uM), C. albicans ATCC2002 (MIC 3 uM), A.flavus IFFI4015 (ND), an
Evidence 14 Activity

Activity

MIC
Antifungal
2.7 µM

Target

B. dysenterium

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

MCCB10104 (MIC 19.5 ug/ml), B. megatherium (MIC 19.5 ug/ml), K. pneumoniae (MIC 9 ug/ml), B. dysenterium (MIC 2.7 uM), C. albicans ATCC2002 (MIC 3 uM), A.flavus IFFI4015 (ND), and P.uticale IFFI2001 (ND). It
Evidence 15 Activity

Activity

MIC
Antifungal
3 µM

Target

Candida albicans ATCC2002

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

. megatherium (MIC 19.5 ug/ml), K. pneumoniae (MIC 9 ug/ml), B. dysenterium (MIC 2.7 uM), C. albicans ATCC2002 (MIC 3 uM), A.flavus IFFI4015 (ND), and P.uticale IFFI2001 (ND). It also has spermicidal effect. act
Evidence 16 Activity

Activity

MIC
Antiparasitic
19.5 µg/mL

Target

Escherichia coli ATCC25922

Source & Reference

dbAMP 3.0 DRAMP

Other

Source Activity Label Source Definition
Antiparasitic
DRAMP antiparasitic activity supported by activity records against parasitic targets. dbAMP 3.0 classified under the Anti-parasitic function class.
Active against E. coli ATCC25922 (MIC 19.5 ug/ml), S. aureus ATCC2592 (MIC 19.5 ug/ml), B. pyocyaneus CMCCB10104 (MIC 19.5 ug/ml), B. megat
Evidence 17 Activity

Activity

MIC
Antiparasitic
19.5 µg/mL

Target

Staphylococcus aureus ATCC2592

Source & Reference

dbAMP 3.0 DRAMP

Other

Active against E. coli ATCC25922 (MIC 19.5 ug/ml), S. aureus ATCC2592 (MIC 19.5 ug/ml), B. pyocyaneus CMCCB10104 (MIC 19.5 ug/ml), B. megatherium (MIC 19.5 ug/ml), K. pneumonia
Evidence 18 Activity

Activity

MIC
Antiparasitic
19.5 µg/mL

Target

B. pyocyaneus CMCCB10104

Source & Reference

dbAMP 3.0 DRAMP

Other

Active against E. coli ATCC25922 (MIC 19.5 ug/ml), S. aureus ATCC2592 (MIC 19.5 ug/ml), B. pyocyaneus CMCCB10104 (MIC 19.5 ug/ml), B. megatherium (MIC 19.5 ug/ml), K. pneumoniae (MIC 9 ug/ml), B. dysenterium (MIC 2.7 uM
Evidence 19 Activity

Activity

MIC
Antiparasitic
19.5 µg/mL

Target

B. megatherium

Source & Reference

dbAMP 3.0 DRAMP

Other

5 ug/ml), S. aureus ATCC2592 (MIC 19.5 ug/ml), B. pyocyaneus CMCCB10104 (MIC 19.5 ug/ml), B. megatherium (MIC 19.5 ug/ml), K. pneumoniae (MIC 9 ug/ml), B. dysenterium (MIC 2.7 uM), C. albicans ATCC2002 (MIC 3 uM
Evidence 20 Activity

Activity

MIC
Antiparasitic
9 µg/mL

Target

Klebsiella pneumoniae

Source & Reference

dbAMP 3.0 DRAMP

Other

19.5 ug/ml), B. pyocyaneus CMCCB10104 (MIC 19.5 ug/ml), B. megatherium (MIC 19.5 ug/ml), K. pneumoniae (MIC 9 ug/ml), B. dysenterium (MIC 2.7 uM), C. albicans ATCC2002 (MIC 3 uM), A.flavus IFFI4015 (ND), an
Evidence 21 Activity

Activity

MIC
Antiparasitic
2.7 µM

Target

B. dysenterium

Source & Reference

dbAMP 3.0 DRAMP

Other

MCCB10104 (MIC 19.5 ug/ml), B. megatherium (MIC 19.5 ug/ml), K. pneumoniae (MIC 9 ug/ml), B. dysenterium (MIC 2.7 uM), C. albicans ATCC2002 (MIC 3 uM), A.flavus IFFI4015 (ND), and P.uticale IFFI2001 (ND). It
Evidence 22 Activity

Activity

MIC
Antiparasitic
3 µM

Target

Candida albicans ATCC2002

Source & Reference

dbAMP 3.0 DRAMP

Other

. megatherium (MIC 19.5 ug/ml), K. pneumoniae (MIC 9 ug/ml), B. dysenterium (MIC 2.7 uM), C. albicans ATCC2002 (MIC 3 uM), A.flavus IFFI4015 (ND), and P.uticale IFFI2001 (ND). It also has spermicidal effect. act
Evidence 23 Activity

Activity

MIC
Antiviral
19.5 µg/mL

Target

Escherichia coli ATCC25922

Source & Reference

dbAMP 3.0 DRAMP DRAVP 2.0

Other

Source Activity Label Source Definition
Antiviral
DRAMP antiviral activity supported by activity records against viral targets. dbAMP 3.0 classified under the Anti-viral function class.
Active against E. coli ATCC25922 (MIC 19.5 ug/ml), S. aureus ATCC2592 (MIC 19.5 ug/ml), B. pyocyaneus CMCCB10104 (MIC 19.5 ug/ml), B. megat
Evidence 24 Activity

Activity

MIC
Antiviral
19.5 µg/mL

Target

Staphylococcus aureus ATCC2592

Source & Reference

dbAMP 3.0 DRAMP DRAVP 2.0

Other

Active against E. coli ATCC25922 (MIC 19.5 ug/ml), S. aureus ATCC2592 (MIC 19.5 ug/ml), B. pyocyaneus CMCCB10104 (MIC 19.5 ug/ml), B. megatherium (MIC 19.5 ug/ml), K. pneumonia
Evidence 25 Activity

Activity

MIC
Antiviral
19.5 µg/mL

Target

B. pyocyaneus CMCCB10104

Source & Reference

dbAMP 3.0 DRAMP DRAVP 2.0

Other

Active against E. coli ATCC25922 (MIC 19.5 ug/ml), S. aureus ATCC2592 (MIC 19.5 ug/ml), B. pyocyaneus CMCCB10104 (MIC 19.5 ug/ml), B. megatherium (MIC 19.5 ug/ml), K. pneumoniae (MIC 9 ug/ml), B. dysenterium (MIC 2.7 uM
Evidence 26 Activity

Activity

MIC
Antiviral
19.5 µg/mL

Target

B. megatherium

Source & Reference

dbAMP 3.0 DRAMP DRAVP 2.0

Other

5 ug/ml), S. aureus ATCC2592 (MIC 19.5 ug/ml), B. pyocyaneus CMCCB10104 (MIC 19.5 ug/ml), B. megatherium (MIC 19.5 ug/ml), K. pneumoniae (MIC 9 ug/ml), B. dysenterium (MIC 2.7 uM), C. albicans ATCC2002 (MIC 3 uM
Evidence 27 Activity

Activity

MIC
Antiviral
9 µg/mL

Target

Klebsiella pneumoniae

Source & Reference

dbAMP 3.0 DRAMP DRAVP 2.0

Other

19.5 ug/ml), B. pyocyaneus CMCCB10104 (MIC 19.5 ug/ml), B. megatherium (MIC 19.5 ug/ml), K. pneumoniae (MIC 9 ug/ml), B. dysenterium (MIC 2.7 uM), C. albicans ATCC2002 (MIC 3 uM), A.flavus IFFI4015 (ND), an
Evidence 28 Activity

Activity

MIC
Antiviral
2.7 µM

Target

B. dysenterium

Source & Reference

dbAMP 3.0 DRAMP DRAVP 2.0

Other

MCCB10104 (MIC 19.5 ug/ml), B. megatherium (MIC 19.5 ug/ml), K. pneumoniae (MIC 9 ug/ml), B. dysenterium (MIC 2.7 uM), C. albicans ATCC2002 (MIC 3 uM), A.flavus IFFI4015 (ND), and P.uticale IFFI2001 (ND). It
Evidence 29 Activity

Activity

MIC
Antiviral
3 µM

Target

Candida albicans ATCC2002

Source & Reference

dbAMP 3.0 DRAMP DRAVP 2.0

Other

. megatherium (MIC 19.5 ug/ml), K. pneumoniae (MIC 9 ug/ml), B. dysenterium (MIC 2.7 uM), C. albicans ATCC2002 (MIC 3 uM), A.flavus IFFI4015 (ND), and P.uticale IFFI2001 (ND). It also has spermicidal effect. act
Evidence 30 Activity

Activity

Hemolysis
Hemolysis
50 µg/mL
[Ref:11835991]Little hemolytic activity at 50 µg/ml against red blood cells

Target

red blood cells

Source & Reference

APD_complete APD_hemolytic
DRAMP4
Eur J Immunol. 2005 Apr 35(4):1220-9.##Peptides. 2002 Mar 23(3):427-435.

Other

Source Activity Label Source Definition
Hemolysis
APD_complete APD-derived hemolytic peptide annotation. APD_hemolytic APD hemolytic peptide annotation.
Evidence 31 Activity

Activity

Toxicity
Hemolytic
Hemolytic_activity: [Ref:11835991]Little hemolytic activity at 50 µg/ml against red blood cells

Target

erythrocytes

Source & Reference

NA
DRAMP
Eur J Immunol. 2005 Apr 35(4):1220-9.##Peptides. 2002 Mar 23(3):427-435.
Evidence 32 Hemolysis

Activity

50 µg/mL
Hemolysis
[Ref:11835991]Little hemolytic activity at 50 µg/ml against red blood cells
Hemolysis

Target

red blood cells

Source & Reference

APD_complete APD_hemolytic
Eur J Immunol. 2005 Apr 35(4):1220-9.##Peptides. 2002 Mar 23(3):427-435.
DRAMP4
APD_complete APD_hemolytic