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Peptide record

TPDB00543

Antibacterial Anticancer Antifungal Antioxidant Antiparasitic Hemolysis Toxicity standard
24 amino acids
Basic Information
3D PDB MODEL
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TPDB00543
Antibacterial Anticancer Antifungal Antioxidant Antiparasitic Hemolysis Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides Functional / health-promoting peptides
AntiBP3 dbAMP DRAMP Peptipedia ACP740 _ACP240 AntiCP 2.0 iACP-DRLF AFP-GFuse Antifungipept CAFPdb APD_complete APD_hemolytic Hemolytic2 ToxinPred 3.0
standard
No
A 24-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
FWGALIKGAAKLIPSVVGLFKKKQ
Physicochemical Analysis
C127H207N31O27
RNDCEHMTY
K
2600.23
11.12
5
0
13
+5
-0.64
0.513
117.92
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
5500
211.52
2
Residue Composition
number
3
A
0
R
0
N
0
D
0
C
0
E
1
Q
3
G
0
H
2
I
3
L
5
K
0
M
2
F
1
P
1
S
0
T
1
W
0
Y
2
V
Amino Acid Distribution
A: 3 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 1 G: 3 H: 0 I: 2 L: 3 K: 5 M: 0 F: 2 P: 1 S: 1 T: 0 W: 1 Y: 0 V: 2
Chemical Descriptors
24
C127H207N31O27
2600.23
11.12
+5
-0.64
0.513
Evidence Records 3 records
Evidence 1 Activity

Activity

Hemolysis
[Ref.11279030]4mm in test condition against horse erythrocytes (A 12-ml sample of blood agar medium was supplemented with 1 ml of sheep or horse erythrocytes. Wells 5 mm in diameter were filled with 20 µl of the peptide solution and placed overnight at 4℃ to allow the diffusion of the hemolytic agent)

Target

horse erythrocytes

Source & Reference

APD_complete APD_hemolytic
DRAMP4
J. Biol. Chem. 2001 276: 17823-17829.

Other

Source Activity Label Source Definition
Hemolysis
APD_complete APD-derived hemolytic peptide annotation. APD_hemolytic APD hemolytic peptide annotation.
Evidence 2 Activity

Activity

Toxicity
Hemolytic
Hemolytic_activity: [Ref.11279030]4mm in test condition against horse erythrocytes (A 12-ml sample of blood agar medium was supplemented with 1 ml of sheep or horse erythrocytes. Wells 5 mm in diameter were filled with 20 µl of the peptide solution and placed overnight at 4℃ to allow the diffusion of the hemolytic agent)

Target

erythrocytes

Source & Reference

NA
DRAMP
J. Biol. Chem. 2001 276: 17823-17829.
Evidence 3 Hemolysis

Activity

[Ref.11279030]4mm in test condition against horse erythrocytes (A 12-ml sample of blood agar medium was supplemented with 1 ml of sheep or horse erythrocytes. Wells 5 mm in diameter were filled with 20 µl of the peptide solution and placed overnight at 4℃ to allow the diffusion of the hemolytic agent)
Hemolysis

Target

horse erythrocytes

Source & Reference

APD_complete APD_hemolytic
J. Biol. Chem. 2001 276: 17823-17829.
DRAMP4
APD_complete APD_hemolytic