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Peptide record

TPDB00526

Antibacterial Anticancer Antifungal Antioxidant Antiparasitic Antiviral standard
56 amino acids
Basic Information
3D PDB MODEL
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TPDB00526
Antibacterial Anticancer Antifungal Antioxidant Antiparasitic Antiviral
Anti-infective peptides Cancer-related peptides Functional / health-promoting peptides
dbAMP DRAMP Peptipedia ACP740 _ACP240 Antifungipept i2APP
standard
No
A 56-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from dbAMP, DRAMP, Peptipedia, and other sources, with an available 3D structural model.
Sequence
FSFKRLKGFAKKLWNSKLARKIRTKGLKYVKNFAKDMLSEGEEAPPAAEPPVEAPQ
Physicochemical Analysis
C292H467N79O77S1
CH
K
6348.46
10.56
13
6
22
+7
16.19
-0.730
64.64
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
6990
110.11
8
Residue Composition
number
7
A
3
R
2
N
1
D
0
C
5
E
1
Q
3
G
0
H
1
I
5
L
10
K
1
M
4
F
5
P
3
S
1
T
1
W
1
Y
2
V
Amino Acid Distribution
A: 7 R: 3 N: 2 D: 1 C: 0 E: 5 Q: 1 G: 3 H: 0 I: 1 L: 5 K: 10 M: 1 F: 4 P: 5 S: 3 T: 1 W: 1 Y: 1 V: 2
Chemical Descriptors
56
C292H467N79O77S1
6348.46
10.56
+7
16.19
-0.730
Evidence Records 12 records
Evidence 1 Activity

Activity

MIC
Antibacterial
0.4-0.8 µM

Target

Escherichia coli NBRC 3972

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class. DRAMP antibacterial activity supported by MIC records against bacterial target organisms.
Im-1 is active against Gram- E. coli NBRC 3972 (MIC 0.4-0.8 uM), Gram+ S. aureus NBRC 13276 (MIC 13-25 uM), and B. subtilis NBRC 3009 (MIC 0.8-1.6 uM). N
Evidence 2 Activity

Activity

MIC
Antibacterial
13-25 µM

Target

Staphylococcus aureus NBRC 13276

Source & Reference

dbAMP DRAMP

Other

Im-1 is active against Gram- E. coli NBRC 3972 (MIC 0.4-0.8 uM), Gram+ S. aureus NBRC 13276 (MIC 13-25 uM), and B. subtilis NBRC 3009 (MIC 0.8-1.6 uM). Note that purified peptide did not show leth
Evidence 3 Activity

Activity

MIC
Antibacterial
0.8-1.6 µM

Target

B. subtilis NBRC 3009

Source & Reference

dbAMP DRAMP

Other

Gram- E. coli NBRC 3972 (MIC 0.4-0.8 uM), Gram+ S. aureus NBRC 13276 (MIC 13-25 uM), and B. subtilis NBRC 3009 (MIC 0.8-1.6 uM). Note that purified peptide did not show lethal effect on the insect even injected at 250
Evidence 4 Activity

Activity

MIC
Antifungal
0.4-0.8 µM

Target

Escherichia coli NBRC 3972

Source & Reference

dbAMP DRAMP Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class. DRAMP antifungal activity supported by activity records against fungal target organisms.
Im-1 is active against Gram- E. coli NBRC 3972 (MIC 0.4-0.8 uM), Gram+ S. aureus NBRC 13276 (MIC 13-25 uM), and B. subtilis NBRC 3009 (MIC 0.8-1.6 uM). N
Evidence 5 Activity

Activity

MIC
Antifungal
13-25 µM

Target

Staphylococcus aureus NBRC 13276

Source & Reference

dbAMP DRAMP Antifungipept

Other

Im-1 is active against Gram- E. coli NBRC 3972 (MIC 0.4-0.8 uM), Gram+ S. aureus NBRC 13276 (MIC 13-25 uM), and B. subtilis NBRC 3009 (MIC 0.8-1.6 uM). Note that purified peptide did not show leth
Evidence 6 Activity

Activity

MIC
Antifungal
0.8-1.6 µM

Target

B. subtilis NBRC 3009

Source & Reference

dbAMP DRAMP Antifungipept

Other

Gram- E. coli NBRC 3972 (MIC 0.4-0.8 uM), Gram+ S. aureus NBRC 13276 (MIC 13-25 uM), and B. subtilis NBRC 3009 (MIC 0.8-1.6 uM). Note that purified peptide did not show lethal effect on the insect even injected at 250
Evidence 7 Activity

Activity

MIC
Antiparasitic
0.4-0.8 µM

Target

Escherichia coli NBRC 3972

Source & Reference

DRAMP

Other

Source Activity Label Source Definition
Antiparasitic
DRAMP antiparasitic activity supported by activity records against parasitic targets.
Im-1 is active against Gram- E. coli NBRC 3972 (MIC 0.4-0.8 uM), Gram+ S. aureus NBRC 13276 (MIC 13-25 uM), and B. subtilis NBRC 3009 (MIC 0.8-1.6 uM). N
Evidence 8 Activity

Activity

MIC
Antiparasitic
13-25 µM

Target

Staphylococcus aureus NBRC 13276

Source & Reference

DRAMP

Other

Im-1 is active against Gram- E. coli NBRC 3972 (MIC 0.4-0.8 uM), Gram+ S. aureus NBRC 13276 (MIC 13-25 uM), and B. subtilis NBRC 3009 (MIC 0.8-1.6 uM). Note that purified peptide did not show leth
Evidence 9 Activity

Activity

MIC
Antiparasitic
0.8-1.6 µM

Target

B. subtilis NBRC 3009

Source & Reference

DRAMP

Other

Gram- E. coli NBRC 3972 (MIC 0.4-0.8 uM), Gram+ S. aureus NBRC 13276 (MIC 13-25 uM), and B. subtilis NBRC 3009 (MIC 0.8-1.6 uM). Note that purified peptide did not show lethal effect on the insect even injected at 250
Evidence 10 Activity

Activity

MIC
Antiviral
0.4-0.8 µM

Target

Escherichia coli NBRC 3972

Source & Reference

DRAMP

Other

Source Activity Label Source Definition
Antiviral
DRAMP antiviral activity supported by activity records against viral targets.
Im-1 is active against Gram- E. coli NBRC 3972 (MIC 0.4-0.8 uM), Gram+ S. aureus NBRC 13276 (MIC 13-25 uM), and B. subtilis NBRC 3009 (MIC 0.8-1.6 uM). N
Evidence 11 Activity

Activity

MIC
Antiviral
13-25 µM

Target

Staphylococcus aureus NBRC 13276

Source & Reference

DRAMP

Other

Im-1 is active against Gram- E. coli NBRC 3972 (MIC 0.4-0.8 uM), Gram+ S. aureus NBRC 13276 (MIC 13-25 uM), and B. subtilis NBRC 3009 (MIC 0.8-1.6 uM). Note that purified peptide did not show leth
Evidence 12 Activity

Activity

MIC
Antiviral
0.8-1.6 µM

Target

B. subtilis NBRC 3009

Source & Reference

DRAMP

Other

Gram- E. coli NBRC 3972 (MIC 0.4-0.8 uM), Gram+ S. aureus NBRC 13276 (MIC 13-25 uM), and B. subtilis NBRC 3009 (MIC 0.8-1.6 uM). Note that purified peptide did not show lethal effect on the insect even injected at 250