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Peptide record

TPDB00514

ACE inhibitor ACE inhibitors Antioxidant standard
4 amino acids
Basic Information
3D PDB MODEL
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TPDB00514
ACE inhibitor
ACE inhibitors Antioxidant
Cardiometabolic peptides Functional / health-promoting peptides
Peptipedia AnOxPePred - 1.0 AODB Multi-AOP
standard
No
A 4-aa standard natural multi-activity (ACE inhibitors and Antioxidant) peptide sequence curated from Peptipedia, AnOxPePred - 1.0, AODB, and other sources, with an available 3D structural model.
Sequence
FPQY
Physicochemical Analysis
C28H35N5O7
ARNDCEGHILKMSTWV
QFPY
553.62
5.94
0
0
2
-0
-1.04
-0.900
0.00
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
1490
269.14
2
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
1
Q
0
G
0
H
0
I
0
L
0
K
0
M
1
F
1
P
0
S
0
T
0
W
1
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 1 G: 0 H: 0 I: 0 L: 0 K: 0 M: 0 F: 1 P: 1 S: 0 T: 0 W: 0 Y: 1 V: 0
Chemical Descriptors
4
C28H35N5O7
553.62
5.94
-0
-1.04
-0.900
553.6054
553.2528
Evidence Records 2 records
Evidence 1 Activity

Activity

IC50
ACE inhibitors
300.70 µM
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001)
ACE inhibitor
ah

Source & Reference

NA
Contreras M. M., Sánchez-Infantes D., Sevilla M. A., Recio I., Amigo L.
Resistance of casein-derived bioactive peptides to simulated gastrointestinal digestión. Int. Dairy J., 32, 71–78, 2013
2013
Journal

Other

4
BIOPEP-UWM database of bioactive peptides SMILES: N[C@@]([H])(Cc1ccccc1)C(=O)N1[C@@]([H])(CCC1)C(=O)N[C@@]([H])(CCC(=O)N)C(=O)N[C@@]([H])(Cc1ccc(O)cc1)C(=O)O InChI=1S/C28H35N5O7.C2H6/c29-20(15-17-5-2-1-3-6-17)27(38)33-14-4-7-23(33)26(37)31-21(12-13-24(30)35)25(36)32-22(28(39)40)16-18-8-10-19(34)11-9-18 1-2/h1-3,5-6,8-11,20-23,34H,4,7,12-16,29H2,(H2,30,35)(H,31,37)(H,32,36)(H,39,40) 1-2H3/t20-,21-,22-,23- /m0./s1 InChIKey=GJKVBKNSOCIWOY-JSEXCYGQSA-N Information concerning Angiotensin-Converting Enzyme (ACE) is available in MEROPS database of proteolytic enzymes (http://merops.sanger.ac.uk/) ID: M02-001 Antioxidative peptide according to the BIOPEP-UWM database of bioactive peptides (ID 9261) the MBPDB database
Evidence 2 Activity

Activity

Antioxidative activity
Antioxidant

Source & Reference

AODB
DFBP
Additional Detail Fields 1 fields
4