Back to search

Peptide record

TPDB00499

Antibacterial Antifungal Antioxidant Hemolysis Toxicity standard
15 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB00499
Antibacterial Antifungal Antioxidant Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides Functional / health-promoting peptides
AntiBP3 Peptipedia Antifungipept CAFPdb dbAMP AODB Multi-AOP APD_complete PD_Hemolysis ToxinPred 3.0
standard
No
A 15-aa standard natural multi-activity (Antibacterial, Antifungal, Antioxidant, and other sources) peptide sequence curated from AntiBP3, Peptipedia, Antifungipept, and other sources, with an available 3D structural model.
Sequence
FLTGLIGGLMKALGK
Physicochemical Analysis
C71H123N17O17S1
RNDCEQHPSWYV
GL
1518.92
10.60
2
0
8
+2
-1.92
1.073
136.67
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
0
0.00
1
Residue Composition
number
1
A
0
R
0
N
0
D
0
C
0
E
0
Q
4
G
0
H
1
I
4
L
2
K
1
M
1
F
0
P
0
S
1
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 1 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 4 H: 0 I: 1 L: 4 K: 2 M: 1 F: 1 P: 0 S: 0 T: 1 W: 0 Y: 0 V: 0
Chemical Descriptors
15
C71H123N17O17S1
1518.92
10.60
+2
-1.92
1.073
Evidence Records 18 records
Evidence 1 Activity

Activity

MIC
Antibacterial
150 µM

Target

S.aureus ATCC 25923

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
Active against S.aureus ATCC 25923 (MIC 150 uM), E. faecalis 981 (MIC 18.8 uM), N. asteroides 201118 (MIC 37.5 uM), P.aeruginosa CGMCC 1.
Evidence 2 Activity

Activity

MIC
Antibacterial
18.8 µM

Target

Enterococcus faecalis 981

Source & Reference

dbAMP

Other

Active against S.aureus ATCC 25923 (MIC 150 uM), E. faecalis 981 (MIC 18.8 uM), N. asteroides 201118 (MIC 37.5 uM), P.aeruginosa CGMCC 1.50 (MIC 150 uM), K.pneumoniae 0
Evidence 3 Activity

Activity

MIC
Antibacterial
37.5 µM

Target

N. asteroides 201118

Source & Reference

dbAMP

Other

Active against S.aureus ATCC 25923 (MIC 150 uM), E. faecalis 981 (MIC 18.8 uM), N. asteroides 201118 (MIC 37.5 uM), P.aeruginosa CGMCC 1.50 (MIC 150 uM), K.pneumoniae 08040724 (MIC 150 uM), E. coli ATCC 2
Evidence 4 Activity

Activity

MIC
Antibacterial
150 µM

Target

K.pneumoniae 08040724

Source & Reference

dbAMP

Other

(MIC 18.8 uM), N. asteroides 201118 (MIC 37.5 uM), P.aeruginosa CGMCC 1.50 (MIC 150 uM), K.pneumoniae 08040724 (MIC 150 uM), E. coli ATCC 25922 (MIC 37.5 uM), C.albicans ATCC 10231 (inactive), and C.glabrata 09090
Evidence 5 Activity

Activity

MIC
Antibacterial
37.5 µM

Target

Escherichia coli ATCC 25922

Source & Reference

dbAMP

Other

(MIC 37.5 uM), P.aeruginosa CGMCC 1.50 (MIC 150 uM), K.pneumoniae 08040724 (MIC 150 uM), E. coli ATCC 25922 (MIC 37.5 uM), C.albicans ATCC 10231 (inactive), and C.glabrata 090902 (MIC 150 uM). Weak antioxidant a
Evidence 6 Activity

Activity

MIC
Antibacterial
150 µM

Target

C.glabrata 090902

Source & Reference

dbAMP

Other

724 (MIC 150 uM), E. coli ATCC 25922 (MIC 37.5 uM), C.albicans ATCC 10231 (inactive), and C.glabrata 090902 (MIC 150 uM). Weak antioxidant activity. Updated 7/2021
Evidence 7 Activity

Activity

MIC
Antifungal
150 µM

Target

S.aureus ATCC 25923

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
Active against S.aureus ATCC 25923 (MIC 150 uM), E. faecalis 981 (MIC 18.8 uM), N. asteroides 201118 (MIC 37.5 uM), P.aeruginosa CGMCC 1.
Evidence 8 Activity

Activity

MIC
Antifungal
18.8 µM

Target

Enterococcus faecalis 981

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Active against S.aureus ATCC 25923 (MIC 150 uM), E. faecalis 981 (MIC 18.8 uM), N. asteroides 201118 (MIC 37.5 uM), P.aeruginosa CGMCC 1.50 (MIC 150 uM), K.pneumoniae 0
Evidence 9 Activity

Activity

MIC
Antifungal
37.5 µM

Target

N. asteroides 201118

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Active against S.aureus ATCC 25923 (MIC 150 uM), E. faecalis 981 (MIC 18.8 uM), N. asteroides 201118 (MIC 37.5 uM), P.aeruginosa CGMCC 1.50 (MIC 150 uM), K.pneumoniae 08040724 (MIC 150 uM), E. coli ATCC 2
Evidence 10 Activity

Activity

MIC
Antifungal
150 µM

Target

K.pneumoniae 08040724

Source & Reference

dbAMP CAFPdb Antifungipept

Other

(MIC 18.8 uM), N. asteroides 201118 (MIC 37.5 uM), P.aeruginosa CGMCC 1.50 (MIC 150 uM), K.pneumoniae 08040724 (MIC 150 uM), E. coli ATCC 25922 (MIC 37.5 uM), C.albicans ATCC 10231 (inactive), and C.glabrata 09090
Evidence 11 Activity

Activity

MIC
Antifungal
37.5 µM

Target

Escherichia coli ATCC 25922

Source & Reference

dbAMP CAFPdb Antifungipept

Other

(MIC 37.5 uM), P.aeruginosa CGMCC 1.50 (MIC 150 uM), K.pneumoniae 08040724 (MIC 150 uM), E. coli ATCC 25922 (MIC 37.5 uM), C.albicans ATCC 10231 (inactive), and C.glabrata 090902 (MIC 150 uM). Weak antioxidant a
Evidence 12 Activity

Activity

MIC
Antifungal
150 µM

Target

C.glabrata 090902

Source & Reference

dbAMP CAFPdb Antifungipept

Other

724 (MIC 150 uM), E. coli ATCC 25922 (MIC 37.5 uM), C.albicans ATCC 10231 (inactive), and C.glabrata 090902 (MIC 150 uM). Weak antioxidant activity. Updated 7/2021
Evidence 13 Activity

Activity

99.8% Hemolysis
Toxicity
200 µM
Hemolytic Cytotoxic
99.8% Hemolysis | 200 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Identification and functional analyses of novel antioxidant peptides and antimicrobial peptides from skin secretions of four East Asian frog species. | Acta Biochim Biophys Sin | 2017
Evidence 14 Activity

Activity

95.3% Hemolysis
Toxicity
100 µM
Hemolytic Cytotoxic
95.3% Hemolysis | 100 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Identification and functional analyses of novel antioxidant peptides and antimicrobial peptides from skin secretions of four East Asian frog species. | Acta Biochim Biophys Sin | 2017
Evidence 15 Activity

Activity

59.0% Hemolysis
Toxicity
50 µM
Hemolytic Cytotoxic
59.0% Hemolysis | 50 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Identification and functional analyses of novel antioxidant peptides and antimicrobial peptides from skin secretions of four East Asian frog species. | Acta Biochim Biophys Sin | 2017
Evidence 16 Activity

Activity

13.0% Hemolysis
Toxicity
25 µM
Hemolytic Cytotoxic
13.0% Hemolysis | 25 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Identification and functional analyses of novel antioxidant peptides and antimicrobial peptides from skin secretions of four East Asian frog species. | Acta Biochim Biophys Sin | 2017
Evidence 17 Activity

Activity

0% Hemolysis
Toxicity
12.5 µM
Hemolytic Cytotoxic
0% Hemolysis | 12.5 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Identification and functional analyses of novel antioxidant peptides and antimicrobial peptides from skin secretions of four East Asian frog species. | Acta Biochim Biophys Sin | 2017
Evidence 18 Hemolysis

Source & Reference

APD_complete PD_Hemolysis
APD_complete PD_Hemolysis

Other

Source Activity Label Source Definition
Hemolysis
APD_complete APD-derived hemolytic peptide annotation.