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Peptide record

TPDB00495

Antibacterial Antifungal Antioxidant Toxicity standard
16 amino acids
Basic Information
3D PDB MODEL
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TPDB00495
Antibacterial Antifungal Antioxidant Toxicity
Anti-infective peptides Toxicity and safety peptides Functional / health-promoting peptides
AntiBP3 Peptipedia AFP-GFuse Antifungipept CAFPdb dbAMP AODB Multi-AOP ToxinPred 3.0
standard
No
A 16-aa standard natural multi-activity (Antibacterial, Antifungal, Antioxidant, and other sources) peptide sequence curated from AntiBP3, Peptipedia, AFP-GFuse, and other sources, with an available 3D structural model.
Sequence
FLPVLGKVIKLVGGLL
Physicochemical Analysis
C83H144N18O17
ARNDCEQHMSTWY
L
1666.17
10.60
2
0
10
+2
-1.57
1.769
200.62
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
0
0.00
0
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
3
G
0
H
1
I
5
L
2
K
0
M
1
F
1
P
0
S
0
T
0
W
0
Y
3
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 3 H: 0 I: 1 L: 5 K: 2 M: 0 F: 1 P: 1 S: 0 T: 0 W: 0 Y: 0 V: 3
Chemical Descriptors
16
C83H144N18O17
1666.17
10.60
+2
-1.57
1.769
Evidence Records 20 records
Evidence 1 Activity

Activity

MIC
Antibacterial
3.1 µM

Target

Staphylococcus aureus ATCC 25923

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
Active against Gram+ S. aureus ATCC 25923 (MIC 3.1 uM), E.faecium 091299 (MIC>100 uM), E. faecalis 981 (MIC 3.1 uM), N. asteroides 201118 (MIC 3
Evidence 2 Activity

Activity

MIC
Antibacterial
>100 µM

Target

E.faecium 091299

Source & Reference

dbAMP

Other

Active against Gram+ S. aureus ATCC 25923 (MIC 3.1 uM), E.faecium 091299 (MIC>100 uM), E. faecalis 981 (MIC 3.1 uM), N. asteroides 201118 (MIC 3.1 uM), Gram- P.aeruginosa CGMC
Evidence 3 Activity

Activity

MIC
Antibacterial
3.1 µM

Target

Enterococcus faecalis 981

Source & Reference

dbAMP

Other

Active against Gram+ S. aureus ATCC 25923 (MIC 3.1 uM), E.faecium 091299 (MIC>100 uM), E. faecalis 981 (MIC 3.1 uM), N. asteroides 201118 (MIC 3.1 uM), Gram- P.aeruginosa CGMCC 1.50 (MIC >100 uM), K.pneumo
Evidence 4 Activity

Activity

MIC
Antibacterial
3.1 µM

Target

N. asteroides 201118

Source & Reference

dbAMP

Other

eus ATCC 25923 (MIC 3.1 uM), E.faecium 091299 (MIC>100 uM), E. faecalis 981 (MIC 3.1 uM), N. asteroides 201118 (MIC 3.1 uM), Gram- P.aeruginosa CGMCC 1.50 (MIC >100 uM), K.pneumoniae 08040724 (MIC >100 uM), E.cloa
Evidence 5 Activity

Activity

MIC
Antibacterial
>100 µM

Target

K.pneumoniae 08040724

Source & Reference

dbAMP

Other

3.1 uM), N. asteroides 201118 (MIC 3.1 uM), Gram- P.aeruginosa CGMCC 1.50 (MIC >100 uM), K.pneumoniae 08040724 (MIC >100 uM), E.cloacae CGMCC 1.57 (MIC >100 uM), E.coli ATCC 25922 (MIC >100 uM), P. faecalis X29 (MI
Evidence 6 Activity

Activity

MIC
Antibacterial
>100 µM

Target

E.coli ATCC 25922

Source & Reference

dbAMP

Other

0 (MIC >100 uM), K.pneumoniae 08040724 (MIC >100 uM), E.cloacae CGMCC 1.57 (MIC >100 uM), E.coli ATCC 25922 (MIC >100 uM), P. faecalis X29 (MIC 50 uM), and fungi C. glabrata 090902 (MIC 50 uM), C.albicans(ATCC 1
Evidence 7 Activity

Activity

MIC
Antibacterial
50 µM

Target

P. faecalis X29

Source & Reference

dbAMP

Other

40724 (MIC >100 uM), E.cloacae CGMCC 1.57 (MIC >100 uM), E.coli ATCC 25922 (MIC >100 uM), P. faecalis X29 (MIC 50 uM), and fungi C. glabrata 090902 (MIC 50 uM), C.albicans(ATCC 10231 (MIC>100 uM). Toxicity:
Evidence 8 Activity

Activity

MIC
Antibacterial
50 µM

Target

C. glabrata 090902

Source & Reference

dbAMP

Other

57 (MIC >100 uM), E.coli ATCC 25922 (MIC >100 uM), P. faecalis X29 (MIC 50 uM), and fungi C. glabrata 090902 (MIC 50 uM), C.albicans(ATCC 10231 (MIC>100 uM). Toxicity: 10% hemolysis at 100 uM, less hemo.lytic.
Evidence 9 Activity

Activity

MIC
Antifungal
3.1 µM

Target

Staphylococcus aureus ATCC 25923

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
Active against Gram+ S. aureus ATCC 25923 (MIC 3.1 uM), E.faecium 091299 (MIC>100 uM), E. faecalis 981 (MIC 3.1 uM), N. asteroides 201118 (MIC 3
Evidence 10 Activity

Activity

MIC
Antifungal
>100 µM

Target

E.faecium 091299

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Active against Gram+ S. aureus ATCC 25923 (MIC 3.1 uM), E.faecium 091299 (MIC>100 uM), E. faecalis 981 (MIC 3.1 uM), N. asteroides 201118 (MIC 3.1 uM), Gram- P.aeruginosa CGMC
Evidence 11 Activity

Activity

MIC
Antifungal
3.1 µM

Target

Enterococcus faecalis 981

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Active against Gram+ S. aureus ATCC 25923 (MIC 3.1 uM), E.faecium 091299 (MIC>100 uM), E. faecalis 981 (MIC 3.1 uM), N. asteroides 201118 (MIC 3.1 uM), Gram- P.aeruginosa CGMCC 1.50 (MIC >100 uM), K.pneumo
Evidence 12 Activity

Activity

MIC
Antifungal
3.1 µM

Target

N. asteroides 201118

Source & Reference

dbAMP CAFPdb Antifungipept

Other

eus ATCC 25923 (MIC 3.1 uM), E.faecium 091299 (MIC>100 uM), E. faecalis 981 (MIC 3.1 uM), N. asteroides 201118 (MIC 3.1 uM), Gram- P.aeruginosa CGMCC 1.50 (MIC >100 uM), K.pneumoniae 08040724 (MIC >100 uM), E.cloa
Evidence 13 Activity

Activity

MIC
Antifungal
>100 µM

Target

K.pneumoniae 08040724

Source & Reference

dbAMP CAFPdb Antifungipept

Other

3.1 uM), N. asteroides 201118 (MIC 3.1 uM), Gram- P.aeruginosa CGMCC 1.50 (MIC >100 uM), K.pneumoniae 08040724 (MIC >100 uM), E.cloacae CGMCC 1.57 (MIC >100 uM), E.coli ATCC 25922 (MIC >100 uM), P. faecalis X29 (MI
Evidence 14 Activity

Activity

MIC
Antifungal
>100 µM

Target

E.coli ATCC 25922

Source & Reference

dbAMP CAFPdb Antifungipept

Other

0 (MIC >100 uM), K.pneumoniae 08040724 (MIC >100 uM), E.cloacae CGMCC 1.57 (MIC >100 uM), E.coli ATCC 25922 (MIC >100 uM), P. faecalis X29 (MIC 50 uM), and fungi C. glabrata 090902 (MIC 50 uM), C.albicans(ATCC 1
Evidence 15 Activity

Activity

MIC
Antifungal
50 µM

Target

P. faecalis X29

Source & Reference

dbAMP CAFPdb Antifungipept

Other

40724 (MIC >100 uM), E.cloacae CGMCC 1.57 (MIC >100 uM), E.coli ATCC 25922 (MIC >100 uM), P. faecalis X29 (MIC 50 uM), and fungi C. glabrata 090902 (MIC 50 uM), C.albicans(ATCC 10231 (MIC>100 uM). Toxicity:
Evidence 16 Activity

Activity

MIC
Antifungal
50 µM

Target

C. glabrata 090902

Source & Reference

dbAMP CAFPdb Antifungipept

Other

57 (MIC >100 uM), E.coli ATCC 25922 (MIC >100 uM), P. faecalis X29 (MIC 50 uM), and fungi C. glabrata 090902 (MIC 50 uM), C.albicans(ATCC 10231 (MIC>100 uM). Toxicity: 10% hemolysis at 100 uM, less hemo.lytic.
Evidence 17 Activity

Activity

4% Hemolysis
Toxicity
6.3 µM
Hemolytic Cytotoxic
4% Hemolysis | 6.3 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Identification of multiple peptides with antioxidant and antimicrobial activities from skin and its secretions of Hylarana taipehensis, Amolops lifanensis, and Amolops granulosus. | Biochimie | 2014
Evidence 18 Activity

Activity

6% Hemolysis
Toxicity
25 µM
Hemolytic Cytotoxic
6% Hemolysis | 25 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Identification of multiple peptides with antioxidant and antimicrobial activities from skin and its secretions of Hylarana taipehensis, Amolops lifanensis, and Amolops granulosus. | Biochimie | 2014
Evidence 19 Activity

Activity

9% Hemolysis
Toxicity
50 µM
Hemolytic Cytotoxic
9% Hemolysis | 50 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Identification of multiple peptides with antioxidant and antimicrobial activities from skin and its secretions of Hylarana taipehensis, Amolops lifanensis, and Amolops granulosus. | Biochimie | 2014
Evidence 20 Activity

Activity

10% Hemolysis
Toxicity
100 µM
Hemolytic Cytotoxic
10% Hemolysis | 100 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Identification of multiple peptides with antioxidant and antimicrobial activities from skin and its secretions of Hylarana taipehensis, Amolops lifanensis, and Amolops granulosus. | Biochimie | 2014