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Peptide record

TPDB00492

Antibacterial Antifungal Antioxidant Hemolysis Toxicity standard
24 amino acids
Basic Information
3D PDB MODEL
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TPDB00492
Antibacterial Antifungal Antioxidant Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides Functional / health-promoting peptides
AntiBP3 Peptipedia AFP-GFuse Antifungipept CAFPdb dbAMP AODB APD_complete APD_hemolytic HemoPI Hemolytic2 PD_Hemolysis ToxinPred 3.0
standard
No
A 24-aa standard natural multi-activity (Antibacterial, Antifungal, Antioxidant, and other sources) peptide sequence curated from AntiBP3, Peptipedia, AFP-GFuse, and other sources, with an available 3D structural model.
Sequence
FLPGLIKAAVGVGSTILCKITKKC
Physicochemical Analysis
C113H198N28O28S2
RNDEQHMWY
K
2461.11
10.17
4
0
11
+4
0.43
1.004
130.00
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
125
5.08
5
Residue Composition
number
2
A
0
R
0
N
0
D
2
C
0
E
0
Q
3
G
0
H
3
I
3
L
4
K
0
M
1
F
1
P
1
S
2
T
0
W
0
Y
2
V
Amino Acid Distribution
A: 2 R: 0 N: 0 D: 0 C: 2 E: 0 Q: 0 G: 3 H: 0 I: 3 L: 3 K: 4 M: 0 F: 1 P: 1 S: 1 T: 2 W: 0 Y: 0 V: 2
Chemical Descriptors
24
C113H198N28O28S2
2461.11
10.17
+4
0.43
1.004
Evidence Records 22 records
Evidence 1 Activity

Activity

MIC
Antibacterial
12.5 µM

Target

Staphylococcus aureus ATCC 25923

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
Active against Gram+ S. aureus ATCC 25923 (MIC 12.5 uM), E.faecium 091299 (MIC>100 uM), E. faecalis 981 (MIC 6.3 uM), N. asteroides 201118 (MIC 6
Evidence 2 Activity

Activity

MIC
Antibacterial
>100 µM

Target

E.faecium 091299

Source & Reference

dbAMP

Other

Active against Gram+ S. aureus ATCC 25923 (MIC 12.5 uM), E.faecium 091299 (MIC>100 uM), E. faecalis 981 (MIC 6.3 uM), N. asteroides 201118 (MIC 6.3 uM), Gram- P.aeruginosa CGMC
Evidence 3 Activity

Activity

MIC
Antibacterial
6.3 µM

Target

Enterococcus faecalis 981

Source & Reference

dbAMP

Other

Active against Gram+ S. aureus ATCC 25923 (MIC 12.5 uM), E.faecium 091299 (MIC>100 uM), E. faecalis 981 (MIC 6.3 uM), N. asteroides 201118 (MIC 6.3 uM), Gram- P.aeruginosa CGMCC 1.50 (MIC >100 uM), K.pneumo
Evidence 4 Activity

Activity

MIC
Antibacterial
6.3 µM

Target

N. asteroides 201118

Source & Reference

dbAMP

Other

us ATCC 25923 (MIC 12.5 uM), E.faecium 091299 (MIC>100 uM), E. faecalis 981 (MIC 6.3 uM), N. asteroides 201118 (MIC 6.3 uM), Gram- P.aeruginosa CGMCC 1.50 (MIC >100 uM), K.pneumoniae 08040724 (MIC >100 uM), E.cloa
Evidence 5 Activity

Activity

MIC
Antibacterial
>100 µM

Target

K.pneumoniae 08040724

Source & Reference

dbAMP

Other

6.3 uM), N. asteroides 201118 (MIC 6.3 uM), Gram- P.aeruginosa CGMCC 1.50 (MIC >100 uM), K.pneumoniae 08040724 (MIC >100 uM), E.cloacae CGMCC 1.57 (MIC >100 uM), E.coli ATCC 25922 (MIC >100 uM), P. faecalis X29 (MI
Evidence 6 Activity

Activity

MIC
Antibacterial
>100 µM

Target

E.coli ATCC 25922

Source & Reference

dbAMP

Other

0 (MIC >100 uM), K.pneumoniae 08040724 (MIC >100 uM), E.cloacae CGMCC 1.57 (MIC >100 uM), E.coli ATCC 25922 (MIC >100 uM), P. faecalis X29 (MIC 50 uM), and fungi C. glabrata 090902 (MIC 12.5 uM), C.albicans(ATCC
Evidence 7 Activity

Activity

MIC
Antibacterial
50 µM

Target

P. faecalis X29

Source & Reference

dbAMP

Other

40724 (MIC >100 uM), E.cloacae CGMCC 1.57 (MIC >100 uM), E.coli ATCC 25922 (MIC >100 uM), P. faecalis X29 (MIC 50 uM), and fungi C. glabrata 090902 (MIC 12.5 uM), C.albicans(ATCC 10231 (MIC>100 uM).
Evidence 8 Activity

Activity

MIC
Antibacterial
12.5 µM

Target

C. glabrata 090902

Source & Reference

dbAMP

Other

57 (MIC >100 uM), E.coli ATCC 25922 (MIC >100 uM), P. faecalis X29 (MIC 50 uM), and fungi C. glabrata 090902 (MIC 12.5 uM), C.albicans(ATCC 10231 (MIC>100 uM).
Evidence 9 Activity

Activity

MIC
Antifungal
12.5 µM

Target

Staphylococcus aureus ATCC 25923

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
Active against Gram+ S. aureus ATCC 25923 (MIC 12.5 uM), E.faecium 091299 (MIC>100 uM), E. faecalis 981 (MIC 6.3 uM), N. asteroides 201118 (MIC 6
Evidence 10 Activity

Activity

MIC
Antifungal
>100 µM

Target

E.faecium 091299

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Active against Gram+ S. aureus ATCC 25923 (MIC 12.5 uM), E.faecium 091299 (MIC>100 uM), E. faecalis 981 (MIC 6.3 uM), N. asteroides 201118 (MIC 6.3 uM), Gram- P.aeruginosa CGMC
Evidence 11 Activity

Activity

MIC
Antifungal
6.3 µM

Target

Enterococcus faecalis 981

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Active against Gram+ S. aureus ATCC 25923 (MIC 12.5 uM), E.faecium 091299 (MIC>100 uM), E. faecalis 981 (MIC 6.3 uM), N. asteroides 201118 (MIC 6.3 uM), Gram- P.aeruginosa CGMCC 1.50 (MIC >100 uM), K.pneumo
Evidence 12 Activity

Activity

MIC
Antifungal
6.3 µM

Target

N. asteroides 201118

Source & Reference

dbAMP CAFPdb Antifungipept

Other

us ATCC 25923 (MIC 12.5 uM), E.faecium 091299 (MIC>100 uM), E. faecalis 981 (MIC 6.3 uM), N. asteroides 201118 (MIC 6.3 uM), Gram- P.aeruginosa CGMCC 1.50 (MIC >100 uM), K.pneumoniae 08040724 (MIC >100 uM), E.cloa
Evidence 13 Activity

Activity

MIC
Antifungal
>100 µM

Target

K.pneumoniae 08040724

Source & Reference

dbAMP CAFPdb Antifungipept

Other

6.3 uM), N. asteroides 201118 (MIC 6.3 uM), Gram- P.aeruginosa CGMCC 1.50 (MIC >100 uM), K.pneumoniae 08040724 (MIC >100 uM), E.cloacae CGMCC 1.57 (MIC >100 uM), E.coli ATCC 25922 (MIC >100 uM), P. faecalis X29 (MI
Evidence 14 Activity

Activity

MIC
Antifungal
>100 µM

Target

E.coli ATCC 25922

Source & Reference

dbAMP CAFPdb Antifungipept

Other

0 (MIC >100 uM), K.pneumoniae 08040724 (MIC >100 uM), E.cloacae CGMCC 1.57 (MIC >100 uM), E.coli ATCC 25922 (MIC >100 uM), P. faecalis X29 (MIC 50 uM), and fungi C. glabrata 090902 (MIC 12.5 uM), C.albicans(ATCC
Evidence 15 Activity

Activity

MIC
Antifungal
50 µM

Target

P. faecalis X29

Source & Reference

dbAMP CAFPdb Antifungipept

Other

40724 (MIC >100 uM), E.cloacae CGMCC 1.57 (MIC >100 uM), E.coli ATCC 25922 (MIC >100 uM), P. faecalis X29 (MIC 50 uM), and fungi C. glabrata 090902 (MIC 12.5 uM), C.albicans(ATCC 10231 (MIC>100 uM).
Evidence 16 Activity

Activity

MIC
Antifungal
12.5 µM

Target

C. glabrata 090902

Source & Reference

dbAMP CAFPdb Antifungipept

Other

57 (MIC >100 uM), E.coli ATCC 25922 (MIC >100 uM), P. faecalis X29 (MIC 50 uM), and fungi C. glabrata 090902 (MIC 12.5 uM), C.albicans(ATCC 10231 (MIC>100 uM).
Evidence 17 Activity

Activity

7% Hemolysis
Toxicity
6.3 µM
Hemolytic Cytotoxic
7% Hemolysis | 6.3 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Identification of multiple peptides with antioxidant and antimicrobial activities from skin and its secretions of Hylarana taipehensis, Amolops lifanensis, and Amolops granulosus. | Biochimie | 2014
Evidence 18 Activity

Activity

21% Hemolysis
Toxicity
12.5 µM
Hemolytic Cytotoxic
21% Hemolysis | 12.5 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Identification of multiple peptides with antioxidant and antimicrobial activities from skin and its secretions of Hylarana taipehensis, Amolops lifanensis, and Amolops granulosus. | Biochimie | 2014
Evidence 19 Activity

Activity

34% Hemolysis
Toxicity
25 µM
Hemolytic Cytotoxic
34% Hemolysis | 25 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Identification of multiple peptides with antioxidant and antimicrobial activities from skin and its secretions of Hylarana taipehensis, Amolops lifanensis, and Amolops granulosus. | Biochimie | 2014
Evidence 20 Activity

Activity

44% Hemolysis
Toxicity
50 µM
Hemolytic Cytotoxic
44% Hemolysis | 50 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Identification of multiple peptides with antioxidant and antimicrobial activities from skin and its secretions of Hylarana taipehensis, Amolops lifanensis, and Amolops granulosus. | Biochimie | 2014
Evidence 21 Activity

Activity

50% Hemolysis
Toxicity
100 µM
Hemolytic Cytotoxic
50% Hemolysis | 100 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Identification of multiple peptides with antioxidant and antimicrobial activities from skin and its secretions of Hylarana taipehensis, Amolops lifanensis, and Amolops granulosus. | Biochimie | 2014
Evidence 22 Hemolysis

Source & Reference

APD_complete APD_hemolytic HemoPI PD_Hemolysis
APD_complete APD_hemolytic PD_Hemolysis

Other

Source Activity Label Source Definition
Hemolysis
APD_complete APD-derived hemolytic peptide annotation. APD_hemolytic APD hemolytic peptide annotation.