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Peptide record

TPDB00468

Antibacterial Anticancer Antifungal Antioxidant Antiparasitic Hemolysis Toxicity standard
20 amino acids
Basic Information
3D PDB MODEL
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TPDB00468
Antibacterial Anticancer Antifungal Antioxidant Antiparasitic Hemolysis Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides Functional / health-promoting peptides
AntiBP3 dbAMP DRAMP Peptipedia ACP740 _ACP240 AntiCP 2.0 iACP-DRLF Antifungipept CAFPdb i2APP APD_complete APD_hemolytic Hemolytic2 ToxinPred 3.0
standard
No
A 20-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
FIGTALGIASAIPAIVKLFK
Physicochemical Analysis
C99H164N22O23
RNDCEQHMWY
AI
2030.52
10.60
2
0
13
+2
-2.51
1.545
151.50
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
0
0.00
2
Residue Composition
number
4
A
0
R
0
N
0
D
0
C
0
E
0
Q
2
G
0
H
4
I
2
L
2
K
0
M
2
F
1
P
1
S
1
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 4 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 2 H: 0 I: 4 L: 2 K: 2 M: 0 F: 2 P: 1 S: 1 T: 1 W: 0 Y: 0 V: 1
Chemical Descriptors
20
C99H164N22O23
2030.52
10.60
+2
-2.51
1.545
Evidence Records 3 records
Evidence 1 Activity

Activity

Hemolysis
[Ref.11279030]3mm in test condition against horse erythrocytes (A 12-ml sample of blood agar medium was supplemented with 1 ml of sheep or horse erythrocytes. Wells 5 mm in diameter were filled with 20 µl of the peptide solution and placed overnight at 4℃ to allow the diffusion of the hemolytic agent)

Target

horse erythrocytes

Source & Reference

APD_complete APD_hemolytic
DRAMP4
J. Biol. Chem. 2001 276: 17823-17829.

Other

Source Activity Label Source Definition
Hemolysis
APD_complete APD-derived hemolytic peptide annotation. APD_hemolytic APD hemolytic peptide annotation.
Evidence 2 Activity

Activity

Toxicity
Hemolytic
Hemolytic_activity: [Ref.11279030]3mm in test condition against horse erythrocytes (A 12-ml sample of blood agar medium was supplemented with 1 ml of sheep or horse erythrocytes. Wells 5 mm in diameter were filled with 20 µl of the peptide solution and placed overnight at 4℃ to allow the diffusion of the hemolytic agent)

Target

erythrocytes

Source & Reference

NA
DRAMP
J. Biol. Chem. 2001 276: 17823-17829.
Evidence 3 Hemolysis

Activity

[Ref.11279030]3mm in test condition against horse erythrocytes (A 12-ml sample of blood agar medium was supplemented with 1 ml of sheep or horse erythrocytes. Wells 5 mm in diameter were filled with 20 µl of the peptide solution and placed overnight at 4℃ to allow the diffusion of the hemolytic agent)
Hemolysis

Target

horse erythrocytes

Source & Reference

APD_complete APD_hemolytic
J. Biol. Chem. 2001 276: 17823-17829.
DRAMP4
APD_complete APD_hemolytic