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Peptide record

TPDB00257

ACE inhibitor ACE inhibitors Antioxidant standard
6 amino acids
Basic Information
3D PDB MODEL
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TPDB00257
ACE inhibitor
ACE inhibitors Antioxidant
Cardiometabolic peptides Functional / health-promoting peptides
pep-lab Peptipedia AnOxPePred - 1.0 AODB AoXpDb Multi-AOP
standard
No
A 6-aa standard natural multi-activity (ACE inhibitors and Antioxidant) peptide sequence curated from pep-lab, Peptipedia, AnOxPePred - 1.0, and other sources, with an available 3D structural model.
Sequence
DGVVYY
Physicochemical Analysis
C34H46N6O11
ARNCEQHILKMFPSTW
YV
714.77
3.10
0
1
4
-1
-0.50
0.317
96.67
Mammalian: 1.1 hour Yeast: 3 min E.coli: >10 hour
2980
416.92
2
Residue Composition
number
0
A
0
R
0
N
1
D
0
C
0
E
0
Q
1
G
0
H
0
I
0
L
0
K
0
M
0
F
0
P
0
S
0
T
0
W
2
Y
2
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 1 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 0 L: 0 K: 0 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 2 V: 2
Chemical Descriptors
6
C34H46N6O11
714.77
3.10
-1
-0.50
0.317
714.7608
714.3213
Evidence Records 2 records
Evidence 1 Activity

Activity

IC50
ACE inhibitors
2.00 µM
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001)
ACE inhibitor
ah

Source & Reference

NA
Moayedi A., Mora L., Aristoy M. C., Safari M., Hashemi M., Toldra F.
Peptidomic analysis of antioxidant and ACE-inhibitory peptides obtained from tomato waste proteins fermented using Bacillus subtilis. Food Chemistry 250 (2018), 180-187.
2018
Journal

Other

6
BIOPEP-UWM database of bioactive peptides SMILES: N[C@@]([H])(CC(=O)O)C(=O)NCC(=O)N[C@@]([H])(C(C)C)C(=O)N[C@@]([H])(C(C)C)C(=O)N[C@@]([H])(Cc1ccc(O)cc1)C(=O)N[C@@]([H])(Cc1ccc(O)cc1)C(=O)O InChI=1S/C34H46N6O11/c1-17(2)28(39-26(43)16-36-30(46)23(35)15-27(44)45)33(49)40-29(18(3)4)32(48)37-24(13-19-5-9-21(41)10-6-19)31(47)38-25(34(50)51)14-20-7-11-22(42)12-8-20/h5-12,17-18,23-25,28-29,41-42H,13-16,35H2,1-4H3,(H,36,46)(H,37,48)(H,38,47)(H,39,43)(H,40,49)(H,44,45)(H,50,51)/t23-,24-,25-,28-,29-/m0/s1 InChIKey: XURXWEYYWCTRGO-ROFHDDJXSA-N
Evidence 2 Activity

Activity

Antioxidative activity
Antioxidant

Source & Reference

AODB AoXpDb
DFBP
Additional Detail Fields 1 fields
6