Back to search

Peptide record

TPDB00225

Antibacterial Antifungal Antioxidant Toxicity standard
21 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB00225
Antibacterial Antifungal Antioxidant Toxicity
Anti-infective peptides Toxicity and safety peptides Functional / health-promoting peptides
AntiBP3 Peptipedia Antifungipept CAFPdb dbAMP AODB ToxinPred 3.0
standard
No
A 21-aa standard natural multi-activity (Antibacterial, Antifungal, Antioxidant, and other sources) peptide sequence curated from AntiBP3, Peptipedia, Antifungipept, and other sources, with an available 3D structural model.
Sequence
CVVSSGWKWNYKIRCKLTGNC
Physicochemical Analysis
C108H169N31O28S3
ADEQHMFP
CK
2445.90
9.66
4
0
7
+4
-1.05
-0.248
64.76
Mammalian: 1.2 hour Yeast: >20 hour E.coli: >10 hour
12615
515.76
9
Residue Composition
number
0
A
1
R
2
N
0
D
3
C
0
E
0
Q
2
G
0
H
1
I
1
L
3
K
0
M
0
F
0
P
2
S
1
T
2
W
1
Y
2
V
Amino Acid Distribution
A: 0 R: 1 N: 2 D: 0 C: 3 E: 0 Q: 0 G: 2 H: 0 I: 1 L: 1 K: 3 M: 0 F: 0 P: 0 S: 2 T: 1 W: 2 Y: 1 V: 2
Chemical Descriptors
21
C108H169N31O28S3
2445.90
9.66
+4
-1.05
-0.248
Evidence Records 7 records
Evidence 1 Activity

Activity

MIC
Antibacterial
4.7 µM

Target

Staphylococcus aureus ATCC 25923

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
Active against S. aureus ATCC 25923 (MIC 4.7 uM), E.faecalis 981 (inactive), N. asteroides 201118 (MIC 18.8 uM), P.aeruginosa CGMCC 1.50 (
Evidence 2 Activity

Activity

MIC
Antibacterial
18.8 µM

Target

N. asteroides 201118

Source & Reference

dbAMP

Other

Active against S. aureus ATCC 25923 (MIC 4.7 uM), E.faecalis 981 (inactive), N. asteroides 201118 (MIC 18.8 uM), P.aeruginosa CGMCC 1.50 (inactive), K.pneumoniae 08040724 (inactive), E.coli ATCC 25922
Evidence 3 Activity

Activity

MIC
Antifungal
4.7 µM

Target

Staphylococcus aureus ATCC 25923

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
Active against S. aureus ATCC 25923 (MIC 4.7 uM), E.faecalis 981 (inactive), N. asteroides 201118 (MIC 18.8 uM), P.aeruginosa CGMCC 1.50 (
Evidence 4 Activity

Activity

MIC
Antifungal
18.8 µM

Target

N. asteroides 201118

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Active against S. aureus ATCC 25923 (MIC 4.7 uM), E.faecalis 981 (inactive), N. asteroides 201118 (MIC 18.8 uM), P.aeruginosa CGMCC 1.50 (inactive), K.pneumoniae 08040724 (inactive), E.coli ATCC 25922
Evidence 5 Activity

Activity

8.6% Hemolysis
Toxicity
200 µM
Hemolytic Cytotoxic
8.6% Hemolysis | 200 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Identification and functional analyses of novel antioxidant peptides and antimicrobial peptides from skin secretions of four East Asian frog species. | Acta Biochim Biophys Sin | 2017
Evidence 6 Activity

Activity

5.7% Hemolysis
Toxicity
100 µM
Hemolytic Cytotoxic
5.7% Hemolysis | 100 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Identification and functional analyses of novel antioxidant peptides and antimicrobial peptides from skin secretions of four East Asian frog species. | Acta Biochim Biophys Sin | 2017
Evidence 7 Activity

Activity

0% Hemolysis
Toxicity
50 µM
Hemolytic Cytotoxic
0% Hemolysis | 50 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Identification and functional analyses of novel antioxidant peptides and antimicrobial peptides from skin secretions of four East Asian frog species. | Acta Biochim Biophys Sin | 2017