Back to search

Peptide record

TPDB00126

ACE inhibitor ACE inhibitors Antioxidant standard
9 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB00126
ACE inhibitor
ACE inhibitors Antioxidant
Cardiometabolic peptides Functional / health-promoting peptides
pep-lab Peptipedia AnOxPePred - 1.0 AODB Multi-AOP
standard
No
A 9-aa standard natural multi-activity (ACE inhibitors and Antioxidant) peptide sequence curated from pep-lab, Peptipedia, AnOxPePred - 1.0, and other sources, with an available 3D structural model.
Sequence
APGAPGPVG
Physicochemical Analysis
C32H51N9O10
RNDCEQHILKMFSTWY
GP
721.81
6.02
0
0
3
-0
1.11
0.200
54.44
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
0
Residue Composition
number
2
A
0
R
0
N
0
D
0
C
0
E
0
Q
3
G
0
H
0
I
0
L
0
K
0
M
0
F
3
P
0
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 2 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 3 H: 0 I: 0 L: 0 K: 0 M: 0 F: 0 P: 3 S: 0 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
9
C32H51N9O10
721.81
6.02
-0
1.11
0.200
721.7996
721.3747
Evidence Records 2 records
Evidence 1 Activity

Activity

IC50
ACE inhibitors
16.20 µM
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001)
ACE inhibitor
ah

Source & Reference

NA
Torkova A., Kononikhin A., Bugrova A., Khotchenkov V., Tsentalovich M., Medvedeva U.
Effect of in vitro gastrointestinal digestion on bioactivity of poultry protein hydrolysate. Curr. Res. Nutr. Food Sci., 4 (SI 2), 77-86, 2016
2016
Journal

Other

9
BIOPEP-UWM database of bioactive peptides SMILES: N[C@@]([H])(C)C(=O)N1[C@@]([H])(CCC1)C(=O)NCC(=O)N[C@@]([H])(C)C(=O)N1[C@@]([H])(CCC1)C(=O)NCC(=O)N1[C@@]([H])(CCC1)C(=O)N[C@@]([H])(C(C)C)C(=O)NCC(=O)O InChI=1S/C32H51N9O10/c1-17(2)26(30(49)36-16-25(44)45)38-29(48)22-10-5-11-39(22)24(43)15-35-28(47)21-9-7-13-41(21)32(51)19(4)37-23(42)14-34-27(46)20-8-6-12-40(20)31(50)18(3)33/h17-22,26H,5-16,33H2,1-4H3,(H,34,46)(H,35,47)(H,36,49)(H,37,42)(H,38,48)(H,44,45)/t18-,19-,20-,21-,22-,26-/m0/s1 InChIKey: OERHLMLTSCZCRB-MWSOCQQISA-N Information concerning Angiotensin-Converting Enzyme (ACE) is available in MEROPS database of proteolytic enzymes (http://merops.sanger.ac.uk/) ID: M02-001
Evidence 2 Activity

Activity

Antioxidative activity
Antioxidant

Source & Reference

AODB
DFBP
Additional Detail Fields 1 fields
9