Peptide record

TPDB00036

Antibacterial Anticancer Antifungal Antioxidant Antiparasitic standard
68 amino acids
Basic Information
3D PDB MODEL
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TPDB00036
Antibacterial Anticancer Antifungal Antioxidant Antiparasitic
Anti-infective peptides Cancer-related peptides Functional / health-promoting peptides
dbAMP DRAMP Peptipedia CancerPPD 2.0 Antifp Antifungipept CAFPdb AODB
standard
No
A 68-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from dbAMP, DRAMP, Peptipedia, and other sources, with an available 3D structural model.
Sequence
AELRCMCIKTTSGIHPKNIQSLEVIGKGTHCNQVEVIATLKDGRKICLDPDAPRIKKIVQKKLAGDES
Physicochemical Analysis
C320H551N95O97S5
FWY
K
7441.77
9.11
14
8
22
+4
24.32
-0.318
97.50
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
250
3.36
16
Residue Composition
number
4
A
3
R
2
N
4
D
4
C
4
E
3
Q
5
G
2
H
8
I
5
L
9
K
1
M
0
F
3
P
3
S
4
T
0
W
0
Y
4
V
Amino Acid Distribution
A: 4 R: 3 N: 2 D: 4 C: 4 E: 4 Q: 3 G: 5 H: 2 I: 8 L: 5 K: 9 M: 1 F: 0 P: 3 S: 3 T: 4 W: 0 Y: 0 V: 4
Chemical Descriptors
68
C320H551N95O97S5
7441.77
9.11
+4
24.32
-0.318
Evidence Records 3 records
Evidence 1 Activity

Activity

Antibacterial

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
Both TCs, but not neutrophil-activating peptide-2 (NAP-2) and connective tissue-activating peptide-III, were active agaiinst B. subtilis, E. coli, S. aureus, and L. lactis and fungicidal against C. neoformans. Killing of B. subtilis by either TC appeared to be very rapid.
Evidence 2 Activity

Activity

Antifungal

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
Both TCs, but not neutrophil-activating peptide-2 (NAP-2) and connective tissue-activating peptide-III, were active agaiinst B. subtilis, E. coli, S. aureus, and L. lactis and fungicidal against C. neoformans. Killing of B. subtilis by either TC appeared to be very rapid.
Evidence 3 Activity

Activity

Antiparasitic

Source & Reference

DRAMP

Other

Both TCs, but not neutrophil-activating peptide-2 (NAP-2) and connective tissue-activating peptide-III, were active agaiinst B. subtilis, E. coli, S. aureus, and L. lactis and fungicidal against C. neoformans. Killing of B. subtilis by either TC appeared to be very rapid.